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The Underhydration Problem: There is an underlying hidden phenomenon commonly occurring in most of our patients. Identification and modification of underhydration can improve your patient outcomes.

Understanding Scar Tissue: A review of scar tissue physiology will prepare the doctor to revisit and improve how to support injury healing in their patients.

Clinical Applications of Cartilage Physiology: A review of cartilage tissue physiology will prepare the doctor to revisit and improve how to support acute conditions are well as prevention and maintenance of your patients’ joint health.

Solving for Posture: You will review in depth negative effects of chronic postural distortions and learn simple interventions to incorporate into your practice to compliment your chiropractic adjustments.

Osteoporosis: We are going to discuss osteoporosis risk factors, imaging modalities, especially as it relates to vertebral compression fracture, and prevention. Then bring it all together to give the doctor better management options for your patients with low bone density.

The Effects of the Vertebral Subluxation Complex: After this in depth look at the neurophysiology of abnormal movement the chiropractor will appreciate the amazing effects the restoration of movement by chiropractic adjustment has on their patients’ health.

Perspectives on Peripheral Neuropathy: After taking this course the chiropractor will have an understanding of current theories behind peripheral neuropathy and additional options for management of this condition for their patients.

What Did You Do Scenarios: These short clinical case studies give the chiropractor a chance to use their knowledge in decision making in a variety of circumstances.

The Underhydration Problem

I .’Under-Hydration’ defined

II. How this shows up in everyday practice
A. Muscle spasm
B. Constipation
C. Plantar Fasciitis

III. Reasons
A. low water intake
B. Processed foods
C. mineral deficiency
D. caffiene
E. Alcohol
F. Blood sugar imbalance
G. Adrenal fatigue

IV. Solutions

Clinical Applications of Cartilage Physiology


I. 3 types of Cartilage
A. hyalin
B. elastic
C. fibrocartilage

II. Cartilage is hydrophilic: Structure
A. Chondrocytes in an extracellular matrix.
B. Chondrocytes synthesize collagen and proteoglycans.
C. Chondrocytes dependent on long range diffusion of nutrients via synovial fluid.
D. avascular, alymphatic, aneural

III. Joint Anatomy
A.Histologically the three joints in the body are fibrous, cartilaginous, and synovial.
B. Functionally the three types of joints are synarthrosis (immovable), amphiarthrosis (slightly moveable), and diarthrosis (freely moveable).
C. The two classification schemes correlate: synarthroses are fibrous, amphiarthroses are cartilaginous, and diarthroses are synovial.
D. Synovial joints are often further classified by the type of movements they permit, which we will not cover here
1. Synovial joints
a) Joint capsule is a fibrous connective tissue that is attached to each participating bone just beyond its articulating surface.
b) Synovium/Synovial membrane
1) Synovium produces synovial fluid Inner layer has villi like small intestine
2) Joints contain relatively little synovial fluid.

IV. Degradation
A. Trauma
1. Acute
2. Repetitive strain
3. Effects
a) Damage= release of cytokines = inflammation
b) Avascular, aneural, alymphatic
c) Osteoarthritis affects whole joint, but primarily hyaline cartilage.
d) Study: hardening of bone leads to degradation of cartilage = viscious cycle.

V. Osteoarthritis
A. Age related vs Secondary to trauma
1. 20 yo vs 80 yo
2. what is the definition of ‘trauma’
3. Chiropractic vs medical view

VI. Role of Chiropractic in maintaining synovial joint health
A. adjustments = better balanced movement
1. intersegmental
2. global movements
3. ROM both local and regional

B. Other factors
C. Nutrition
1. anti-inflammatory diet
2. nutritional supplementation
3. How to navigate all the options
4. Hydration

VII. Clinical Uses
A. Joints
1. Facet Joints
2. SI joints
3. Knees
4. Shoulders
B. Joint inflammation is a different type of pain and often harder to resolve than muscle ache

Understanding Scar Tissue

I. Causes of Damage

II. Physiology of scar tissue formation
A. Non-dividing cells
B. Role of Collagen

III. Stages of Wound/Injury Healing
A. Inflammatory
B. Proliferative/Regenerative
C. ReModulation/Maturation/Remodeling

IV. Nutritional Supplements to consider:

V. Implications
A. Consider the tissues injured: muscle, ligament, tendon, disc (or all of them)
B. Complex structures= uneven, incomplete tearing (microscopic)
C. Have realistic timeframes for healing
D. Educate: prepare for worst, hope for the best
E. Application:
F. Patient examples:

Solving for Posture

I. We use a tremendous amount of energy fighting the effects of gravity.

II. Posture has a long list of negative affects on our health

III. Tech neck is even worse than what we have seen traditionally

IV. Weight of the head= 10 lbs per inch

V. Effects:

VI. Muscle
A.Upper Cross Syndrome
1. Description
2. Intervention
B. Lower Cross Syndrome
1. Description
2. Intervention

VII. Fascia
A. Connective tissue envelope
B. The fascia’s function

VIII. Good News
A. most people have
B. you can still address this issue effectively with a fairly easy home rehab program
C. Do not have to spend a lot of time on this.
D. Simple, but works really well.

Osteoporosis

I. Definition
A. The big picture first
1. Bone fractures, particularly in the spine or hip, are the most serious complications of osteoporosis.
2. Hip fractures often are caused by a fall and can result in disability and even an increased risk of death within the first year after the injury.
3. Vertebral body fractures

II. Physiology Review
A. Bone is a combination of protein (mainly collagen) and minerals
B. Your bones are in a constant state of renewal
C. How likely you are to develop osteoporosis depends partly on how much bone mass you attained in your youth.

III. Risks
A. A number of factors can increase the likelihood that you’ll develop osteoporosis — including your age, race, lifestyle choices, and medical conditions and treatments.
B. Unchangeable: Some risk factors for osteoporosis are out of your control, including:
1. Your sex. Women are much more likely to develop osteoporosis than are men.
2. Age.
3. Race.
4. Family history.
5. Body frame size.
6. Hormone levels

C. Dietary factors
1. Low calcium intake.
2. Eating disorders
3. Gastrointestinal surgery.

D. Steroids and other medications
E. Osteoporosis has also been associated with medications used to combat or prevent:
1.Seizures
2. Gastric reflux
3. Cancer
F. Medical conditions: The risk of osteoporosis is higher in people who have certain medical problems
G. Lifestyle choices

IV. Based on all of the above it can inform your imaging considerations
A. acute pain may be fracture
B. refer for evaluation of Bone Mineral Density (BMD)
C. adjusting technique of choice
D. diet, exercise, supplementation

V. Diagnosis of OP:
A. Plain film radiography (X-ray)
B. CT Scan
C. DEXA scan: Dual x-ray absorptiometry

VI. Imaging Overview for OP concerns: Vertebral Compression Fracture and Hip fracture

A. Plain Film Radiography (x-ray):
1. pros:
2. cons:
3. Considerations for VCF
4. Hallmark Xray findings of VCF:
5. VCF also needs to be differentiated from other possibilities
6. Hip fracture
a) Types of Hip Fracture
b) Femoral neck (approx 50%)
c) Intertrochanteric (approx 45%)
d) Subtrochanteric (approx 5%)
e) X-ray findings
B. CT scan
1. Spine: detects vacuum sign better than x-ray
2. spine and hip both
C. MRI
1. Spine
2. Hip
D. Bone scan (scintigraphy w/ Technitium99)
E. Chiropractic considerations for OP:

VII. Prevention

The Effects of Vertebral Subluxations: a neurologic perspective

I. Philosophy
The 33 Principles of Chiropractic are chiropractic’s core foundational philosophical tenants
This may not sound very ‘Science-y’ to many modern day scientists, researchers, and physicians, however:

II. Science: Neurology Basics
A. Types of mechanoreceptors (I-IV)
B. Mechanoreceptor stimulation (movement of joints) brain affects
C. These extensive connections means movement positively affects
1. movement, muscle tone, posture, balance, positively affect emotions, coordinates visceral functions, improves immunity, learning, supports endocrine balance, coordinating/organizing thought
D. Afferent input is a basic nutrient that the brain needs for proper function and regulation of the human experience
E. Mechanoreceptor stimulation reduces nociception
F. It is well known and understood, not just in chiropractic…
1. Abnormal joint position and abnormal joint movement causes:

III. Also known: Mechanoreceptors are very dense in suboccipitals muscles, intersegmental spinal muscles, TMJ, and atlanto-occipital joint.

IV. The nervous system has a plasticity to it.
A. Plasticity has been defined
B. PNS sensitization occurs from mechanoreception/nociception imbalance
C. C fibers proliferate

V. These are all well-known hard neurologic, anatomic, physiologic facts
A. Therefore Subluxations are
1. chronic stressor that stimulate many brain areas
2. Deep dive on the Cerebellum
3. Pain is not reliable indicator of need for care (we known this)
B. Regardless of technique DC adjustments work
1. effects
2. reasons
C. If DC adjustments are so beneficial than why are they so hard for many of our patients to hold?

Perspectives on Peripheral Neuropathy

I. Background

II. Need for intervention b/c chronic condition
A. Not well addressed by available traditional methods
B. Prevalance

III. New Perspectives
A. PN= caused by ischemia
1. lack of dilation of arterioles= lack of oxygen and healing/everyday nutrients and removal of normal waste products.
2. Reasons
a) Nitric oxide cycle interruption
1) Diabetes, chemo, toxins

IV. Where do we as DC’s fit in?

V. Case Examples:
A. Chemo
B. B12 def neuropathy post gastric bypass
C. IBS = nutrient deficiency
D. Vegetarian
E. statin drugs, or even high doses of red yeast rice.

VI. Observations

VII. General Considerations

VIII. Neuropathy specific nutritional supplements

“What Would You Do’? Patient Scenarios

I. Roofing Contractor Supervisor: Slipped on ice in someone’s backyard, hit head. Unconscious for 4 hours

II. Guy shows up with a right elbow the size of an orange. It is dripping yellow.

III. You see a large bump on the back of your patient’s neck. It is yellow and oozing. He is diabetic.

IV. Pt shows up with a cast/boot and crutches

V. Patient comes in intoxicated and wants to wrestle…

VI. 19 yo male. Wrestling with friend. Pushed into a cement wall. He has Klienfelter’s.

VII. 75 yo male walks into your office reporting right arm and hand mm spasms and lack of control. BP: 88/66, P: 65; slower communication

VIII. Painless limp in a 5 yo boy

IX. 18 mo old boy won’t bear weight on leg

X. 18 mo old girl has pain and won’t lift arm after fall off of bed

XI. 14 yo female soccer player with heel pain

XII. Teenage swimmer shows up with px in upper traps and numb hands

XIII. 15 yo male hockey player with local LBP

XIV. When you suspect labrum tear

XV. Pregnant patient presents with severe pubic bone pain post MVA:

XVI. Elderly patient falls: need to consider…

I. Underhydration 1. Popkin BM, D’Anci KE, Rosenberg IH. Water, hydration, and health. Nutr Rev. 2010 Aug;68(8):439-58. doi: 10.1111/j.1753-4887.2010.00304.x. PMID: 20646222; PMCID: PMC2908954.
2. Liska D, Mah E, Brisbois T, Barrios PL, Baker LB, Spriet LL. Narrative Review of Hydration and Selected Health Outcomes in the General Population. Nutrients. 2019 Jan 1;11(1):70. doi: 10.3390/nu11010070. PMID: 30609670; PMCID: PMC6356561.
3. Institute of Medicine (US) Committee on Military Nutrition Research. Caffeine for the Sustainment of Mental Task Performance: Formulations for Military Operations. Washington (DC): National Academies Press (US); 2001. 2, Pharmacology of Caffeine.
4. Azzouz LL, Sharma S. Physiology, Large Intestine. [Updated 2022 Aug 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507857/
5. Dutt M, Wehrle CJ, Jialal I. Physiology, Adrenal Gland. [Updated 2022 May 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537260/

II. Clinical Applications of Cartilage Physiology 1.Lou-Ren, C, et al. (21 Oct 2022). Anatomy, Cartilage. NCBI Bookshelf. 2021.
2. Yochum, T., Rowe, L., Essentials of Skeletal Radiology, Vol.1, pg.803, Williams & Wilkins, 1996.
3. Salter, R., Textbook of Disorders and Injuries of the Musculoskeletal System, 3rd ed., Williams &Wilkins, 1999.
4. Salter, R., Textbook of Disorders and Injuries of the Musculoskeletal System, 3rd ed., pg 20-22, Williams &Wilkins, 1999.

III. Understanding Scar Tissue
1. Grubbs, H. Et al. (21 May, 2022). Wound Physiology. NCBI Bookshelf. 2022.
2. Kollar, T. (17 March, 2020). Mechanosensitive aspects of cell biology in manual scar therapy for deep dermal defects. International Journal of Molecular Sciences. 2020, 21, 2055; dos:10.339/ijms21062055
3. Salter, R., Textbook of Disorders and Injuries of the Musculoskeletal System, 3rd ed., Williams &Wilkins, 1999.

IV. Neuropathy Perspectives
1. West, B. (2011). The implications of statin induced peripheral neuropathy. Journal of Foot and Ankle Research. April 2011.
2. Stuhlinger, M, et al. (November 2001). Homocysteine impairs the nitric oxide synthase pathway. American Heart Association Vol 104, Issue
3. Burke TJ. Infrared Photo Energy May Reduce Neuropathic Pain. Practical Pain Management. 2007;7(6):57-63.
4. Prendergast JJ, Miranda G, Sanchez M. Improvement of Sensory Impairment in Patients with Peripheral Neuropathy. Endocrine Practice. 2004;10:24-30.
5. Delellis S, Carnegie DE, Burke TJ. Improved Sensitivity in Patients with Peripheral Neuropathy: Effects of Monochromatic Infrared Photo Energy. Journal of the American Podiatric Medical Association. 2005; 95(2):143-147.
6. Harkless L, Delellis S, Burke TJ. Improved Foot Sensitivity and Pain Reduction in Patients with Peripheral Neuropathy after Treatment with Monochromatic Infrared Photo Energy-MIRE™. Journal of Diabetes and Its Complications. 2006;20(2):81-87. 28.
7. Mohan IK, Cas UN. Effects of L-arginine-nitric oxide system on chemical induced diabetes mellitus. Free Radic Biol Med. 1998 Nov 1; 25(7):757-65.
8. Zeiher, A.M., Schachinger, V., and Minners, J. Long-Term Cigarette Smoking Impairs Endothelium-Dependent Coronary Arterial Vasodilator Function. Circula-tion. 1995; 92:1094-1100.
9. Fried R, Merrell WC. The Arginine Solution. New York, New York. Warner Books, 1999.

V. What Do You Do Scenarios
1. Radswiki T, Knipe H, Tan W, et al. Spondylolysis. Reference article, Radiopaedia.org (Accessed on 26 Feb 2023) https://doi.org/10.53347/rID-12262
2. Yochum, T., Rowe, L., Essentials of Skeletal Radiology, Vol.1, pg.327-372, Williams & Wilkins, 1996.
3. Ferlin, A. Et al. (March 27, 2010). Osteoporosis in Klinefelter’s syndrome. Mol Hum Reprod. 2010 Jun;16(6):402-10.
4. Chan, D. Et all. (2006 Aug). Genetics of disc degeneration. Eur Spine Journal. 15(Suppl 3);317-325.
5. Burton, Kim., Adams, Michael A.., Dolan, Patricia., Bogduk, Nikolai. The Biomechanics of Back Pain. United Kingdom: Elsevier Health Sciences, 2012.
6. Salter, R., Textbook of Disorders and Injuries of the Musculoskeletal System, 3rd ed., Williams &Wilkins, 1999.

VI. The Effects of Subluxation
1. Chesnut, J., Fourteen foundational premises for the scientific and philosophical validation of the chiropractic wellness paradigm. Victoria Press, 2003.
2. Seaman, D., Winterstein, J., Dysafferentation: A Novel Term to Describe the Neuropathophysiological Effects of Joint Complex DysfunctionJ Manipulative Physiol Ther 1998 (May); 21 (4): 267-280.
3. Gebhart GF. Scientific Issues of Pain and Distress. In: National Research Council (US) Committee on Regulatory Issues in Animal Care and Use. Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held June 22, 2000. Washington (DC): National Academies Press (US); 2000.

VII. Solving for Posture
1. Dalton, E.,Concepts and Corrections For Head, Neck and Back Pain, Myoskeletal “techniques” for Upper Crossed Syndrome, Freedom From Pain Institute, Oklahoma City, OK, 2005.
2. Chaitow, L., Walker DeLany J., Clinical Application of Neuromuscular Techniques : Practical Case Study Exercises, New York : Elsevier Churchill Livingstone, 2005.
3. Seidi F, Bayattork M, Minoonejad H, Andersen LL, Page P. Comprehensive corrective exercise program improves alignment, muscle activation and movement pattern of men with upper crossed syndrome: randomized controlled trial. Sci Rep. 2020 Nov 26;10(1):20688.
4. Richardson, Jull, Hodges, Hides, “Therapeutic Exercise For Spinal Segmental Stabilization In Low Back Pain”. London, UK: Churchhill Livingstone, 1999.
5. Bordoni B, Mahabadi N, Varacallo M. Anatomy, Fascia. [Updated 2022 Jul 18]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-.

VIII. Osteoporosis
1. Morri, M, et al. (2019). One-year mortality after hip fracture surgery and prognostic factors: a prospective cohort study. Scientific Reports.
2. Dimet-Wiley, A, et al. (Jan-Mar 2022). One-Year oostfracture morality rate in older adult with hip fractures relative to other lower extremity fractures. JMIT Aging 2022;5(1):e32683
3. Basaraba, S. (March 17, 2022). Hip fracture dangers and mortality rates. www.verywellhealth.com
4. Pizzorno, L. (August, 2015). Nothing boring about Boron. Integrative Medicine.
5. Panda, et al. (May-June, 2014). Imaging of vertebral fractures. Indian Journal of Endocrinology and Metabolism.
6. Chiodini, I. (June, 2008). Role of cortisol hyper secretion in the pathogenesis of osteoporosis. www.pubmed.com
7. Guzon-Illescas, O., Fernandez, E., et al. (2019). Mortality after osteoporotic hip fracture: incidence, trends, and associated factors. Journal of Orthopedic Surgery and Research.
8. Konig, D. (December 4, 2017). Specific collagen peptides improve bone mineral density and bone markers in postmenopausal women- a randomized controlled study. www.mdpi.com
9. Schnell, S. Et al. (2010). The 1-year mortality of patients treated in a hip fracture program for elders. Geriatric Orthopaedic Surgery and Rehabilitation I(I)6-14.

Kyle Hagel, DC

Dr. Hagel has over 20 years of practice experience with a diverse practice background that includes Evaluation and Management of Auto Injuries, Functional Muscle Evaluation, Sports Medicine, Postural Reeducation, Structural Correction, Disc Injury Management, Spine and Extremity Bracing, Neuropathy Pain Management, Weight Loss, Functional Medicine, and Acupuncture. He also has benefitted greatly from working cooperatively with Physicians, Physician Assistants, and Nurse Practitioners in an integrated clinic for the last 14 years and continues to do so.

Educating patients has always been very important to Dr. Hagel in his practice. Patients that understand their condition make better decisions about their care. He is excited to now be involved in chiropractic continuing education and helping other doctors to do the same for their patients.

Course Content

The Under-Hydration Problem 1 Topic | 1 Quiz
Clinical Applications of Cartilage Physiology 1 Topic | 1 Quiz
Understanding Scar Tissue 1 Topic | 1 Quiz
Solving for Posture 1 Topic | 1 Quiz
Osteoporosis 1 Topic | 1 Quiz
Lesson Content
0% Complete 0/1 Steps
Perspectives on Peripheral Neuropathy 1 Topic | 1 Quiz
‘What Do You Do?’ Patient Scenarios 1 Topic | 1 Quiz